Estrace breast cancer

Vaginal dryness probably results from changes that occur when estrogen levels drop. Low estrogen causes the vagina and surrounding connective tissue to lose elasticity and the tissue that lines the vagina becomes thinner and more fragile. If you're sore from vaginal dryness, you don't want to have sex and if you don't have sex, your vaginal dryness gets worse—a classic catch How does vaginal dryness feel? Itchy is how most women describe it.
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Women's Health Care Physicians

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Estrace: Uses, Dosage & Side Effects -

Some women have also been reluctant to use vaginally applied estrogens, which can ease symptoms like dryness and painful intercourse. Women go through menopause when they stop menstruating, typically between ages 45 and As the ovaries curb production of the hormones estrogen and progesterone in the years leading up to menopause and afterward, women can experience symptoms ranging from irregular periods and vaginal dryness to mood swings and insomnia. Study participants who used vaginal estrogen were less likely to be black or African-American, Hispanic, current smokers, diabetic or obese. When researchers looked just at women who still had a uterus, the results looked even more favorable for vaginal estrogen users. Even so, the findings should reassure women, said Dr. Some women who have avoided vaginal estrogen because they thought it was just as risky as pills may now be able to get relief for previously untreated menopause symptoms, said Dr.
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Using Vaginal Estrogen Not Linked to High Breast Cancer Risk

Estrogen increases the risk that you will develop endometrial cancer cancer of the lining of the uterus [womb]. The longer you use estrogen, the greater the risk that you will develop endometrial cancer. If you have not had a hysterectomy surgery to remove the uterus , you may be given another medication called a progestin to take with vaginal estrogen. This may decrease your risk of developing endometrial cancer but may increase your risk of developing certain other health problems, including breast cancer. Before you begin using vaginal estrogen, tell your doctor if you have or have ever had cancer and if you have unusual vaginal bleeding.
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Vaginal estrogen therapy use was not tied to any increased cardiovascular or cancer risk, an analysis of the Women's Health Initiative WHI Observational study found. Among postmenopausal women ages 50 to 79 with an intact uterus, the risk of invasive breast cancer, colorectal cancer, endometrial cancer, stroke, and pulmonary embolism or deep vein thrombosis was no greater when compared with non-users, according to Carolyn Crandall, MD, of UCLA, and colleagues. The study, online in Menopause , showed no significant risk differences between estrogen users and non-users for individual or overall global index event GIE risks among women who had previously undergone a hysterectomy either GIE adjusted [a]HR 0. Estrogen users with intact uteruses also reported a decreased risk for all-cause mortality, coronary heart disease, fracture, and overall risk of a GIE versus non-users GIE aHR 0. The researchers used participant data from the multicenter WHI study, and identified a total of 45, postmenopausal women who were not using systemic estrogen therapy.
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